Publications

2025

Liver-targeted allergen immunotherapy rapidly and safely induces antigen-specific tolerance to treat allergic airway disease in mice J Emiliano Gómez Medellín, TWM Ung, T Wang, K Chang, … JW Reda … Science Translational Medicine, 17 (794), eadl0406
Activity-attenuated serum albumin-fused interleukin-33 suppresses experimental autoimmune encephalomyelitis E Budina, JW Reda, S Cao, EA Watkins, A Solanki, M Nguyen, … Cell Reports Medicine, 6 (7)
A prometabolite strategy inhibits cardiometabolic disease in an ApoE-/- murine model of atherosclerosis TN Beckman, LR Volpatti, S Norton de Matos, AJ Slezak, JW Reda … JCI insight, 10 (15), e191090

A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice
S Cao, E Budina, MM Raczy, A Solanki, M Nguyen, TN Beckman, JW Reda …
Nature Biomedical Engineering, 1-17
Recombinant Fusions of Antigen with Mediators of Efferocytosis Modulate Antigen-Specific Immune Responses
JW Reda
The University of Chicago
LDL-Binding IL-10 Reduces Vascular Inflammation in Atherosclerotic Mice
LR Volpatti, S Norton de Matos, G Borjas, J Reda, EA Watkins, Z Zhou, …
bioRxiv, 2024.03.04.582839

Topically-applied collagen-binding serum albumin-fused interleukin-4 modulates wound microenvironment in non-healing wounds
AL Lauterbach, RP Wallace, AT Alpar, KC Refvik, JW Reda, A Ishihara, …
NPJ Regenerative Medicine 8 (1), 49
Prophylactic and therapeutic use of synthetically glycosylated antigens to limit allergic airway disease
JEG Medellin, TWM Ung, TR Kurtanich, JW Reda, T Wang, K Chang, …
The Journal of Immunology 210 (1_Supplement), 67.23-67.23
Engineered cytokines target atherosclerotic plaques and locally suppress inflammation
LR Volpatti, J Reda, G Borjas, Z Zhou, Y Fang, J Hubbell
The Journal of Immunology 210 (1_Supplement), 249.08-249.08

Prolonged residence of an albumin–IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis
A Ishihara, J Ishihara, EA Watkins, AC Tremain, M Nguyen, A Solanki, … JW Reda …
Nature Biomedical Engineering 5 (5), 387-398
Polymersomes decorated with the SARS-CoV-2 spike protein receptor-binding domain elicit robust humoral and cellular immunity
LR Volpatti, RP Wallace, S Cao, MM Raczy, R Wang, LT Gray, … JW Reda …
ACS central science 7 (8), 1368-1380
Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant
LT Gray, MM Raczy, PS Briquez, TM Marchell, AT Alpar, RP Wallace, … JW Reda …
Biomaterials 278, 121159
Suppression of rheumatoid arthritis by enhanced lymph node trafficking of engineered interleukin‐10 in murine models
E Yuba, E Budina, K Katsumata, A Ishihara, A Mansurov, … JW Reda …
Arthritis & Rheumatology 73 (5), 769-778
Lymph node-targeted synthetically glycosylated antigen leads to antigen-specific immunological tolerance
CD Maulloo, S Cao, EA Watkins, MM Raczy, AS Solanki, M Nguyen, JW Reda …
Frontiers in Immunology 12, 714842

Enzymatically crosslinked gelatin–laminin hydrogels for applications in neuromuscular tissue engineering
RR Besser, AC Bowles, A Alassaf, D Carbonero, I Claure, E Jones, … JW Reda …
Biomaterials science 8 (2), 591-606
Prolonged residence of an albumin-IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis (Oct, 10.1038/s41551-020-00627-3, 2020)
A Ishihara, J Ishihara, EA Watkins, AC Tremain, M Nguyen, A Solanki, … JW Reda …
Nature Biomedical Engineering 4 (11), 1117-1117